Michael Lengefeld | Zoonotic Spillover

What you need to know

The transmission of animal diseases to humans - zoonotic spillover - is occuring at a faster pace. Greater engagement between social sciences and the biological sciences can contribute to understanding the causes of the increased frequency of what is a statistically rare event.

deforestation causes spillover
Deforestation is a central cause of increased spillover.
Source: Zoë van Dijk for NPR

Bat Colony in Fern Cave, U.S.
Bat Colony in Fern Cave, United States
Source: http://www.fws.gov/ferncave / Wikimedia Commons

What is this research about?

The threat of zoonotic spillover is accelerating. It is estimated that there are over 1.5 million unknown viruses in animal reservoirs; over 600,000 (perhaps as many as 850,000) of these viruses have the potential to infect humans. There is a need for collaboration between social and biological sciences if we are to anticipate and come to terms with zoonotic spillover.


What did the researcher do?

The researchers identified "normal accidents" and "treadmill theory" as concepts that can help societies identify high-risk activities and social structures and processes that heighten the likelihood of zoonotic spillover.

Rainforest in Mexico cleared for Agriculture
Rainforest in Mexico cleared for Agriculture
Source: Jamie Dyer / Wikimedia Commons

Ebola Virus
Electron Micrograph of Ebola Virus
Source: U.S. Centers for Disease Control / Wikimedia Commons

Bushmeat, Ghana
Bushmeat is one of many possible sources of zoonotic spillover. Source: Wikimedia Commons

What did the researcher find?

Two social science concepts are of direct relevance. The first is "normal accidents". Zoonotic spillover is a relatively rare event, and although humans are continually exposed to many potentially infectious pathogens that are derived from other species, most of these microorganisms cannot infect or cause disease in humans. Pathogen spillover events can be linked with human-animal interactions with both natural hosts (such as bats) and intermediate hosts (such as domesticated animals). Although the risk posed by a single encounter or even several hundred encounters is quite low, the chance of spillover grows as the number of encounters grows. If encounters are frequent enough, spillover becomes “normal” – in the Anthropocene these encounters are growing rapidly – and in some cases exponentially.

Several human activities have already caused and elevate the risk of future zoonotic spillover, including climate change, hunting, human migration, landscape changes, livestock trade, and environmental contamination — and these threats have been accelerated with the process of globalization. "Treadmills" can emerge and pose a unique set of environmental threats to biodiversity and land system stability across a range of contexts. A “treadmill of production” is derived from and propels economic competition; a “treadmill of destruction” is fueled by geopolitical and military rivalries. Treadmills of production and destruction accelerate environmental degradation and heighten the risk of zoonotic spillover. The dangers posed by treadmills are istinctive because powerful organizations exploit nature and extract resources in competition with rivals that threaten their organizational vitality – and potentially their survival. These powerful organizations are caught on a treadmill of environmental degradation – and the pace of degradation quickens.


How can you use this research?

Governments and institutions can utilize this knowledge to target interdisciplinary research initiatives aimed at anticipating zoonotic spillover. The social sciences can make valuable contributions. "Normal accidents" demonstrate that rare events are likely to occur with repeated trials over a range of contexts. "Treadmill theory" points to human organizations and processes that generate repeated exposure to novel viruses and heighten the risk of these exposures. Treadmills are a uniquely pernicious type of human activity. Zoonotic spillover is exacerbated by environmental transformation and biodiversity degradation propelled by treadmills of destruction and production.

increasing frequency of pandemics
The frequency of pandemics is increasingly rapidly across the world.

Citation

Lengefeld, Michael, Greg Hooks, and Chad Smith. 2020. “Social Science Contributions to the Study of Zoonotic Spillover: Normal Accidents and Treadmill Theory.” This View of Life (TVOL) Available Here.


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